Pipeline

One platform. Six active programs. One vaccine already in a confirmatory trial.

SurVaxM is validated first in glioblastoma and already moving into four more indications. Behind it, three earlier-stage programs extend the same survivin target into antibody and cell-therapy formats.

Lead asset

SurVaxM® — cancer vaccine

A survivin-targeting peptide-mimic vaccine, in clinical development across six indications from a single confirmed mechanism.

FDA designations already granted

Orphan Drug Designation Fast Track Designation
Completed Active / enrolling Paused Opening soon

Clinical — SurVaxM

Program
Phase 1
Phase 2a
Phase 2b (RCT)
SURVIVENewly diagnosed glioblastoma (GBM)
Phase 1Phase 1
Phase 2aPhase 2aPublished
Phase 2b (RCT)Phase 2b (RCT)Active · Not enrolling
—Metastatic neuroendocrine tumors (NETs)
Phase 1Phase 1
Phase 2a / 2bPhase 2Now open
—Pediatric high-grade glioma
Phase 1Phase 1Paused · Not enrolling
—Multiple myeloma, with lenalidomide
Phase 1Phase 1
—Recurrent glioma
Phase 1Phase 1Completed · published
—Preventative: lung cancer in high-risk smokers
Phase 1Phase 1Opening soon
—Autoimmune disease: myasthenia gravis
Phase 1Phase 1Opening soon

SURVIVE has completed enrollment. For currently enrolled patients, and others asking about SurVaxM outside of a trial, see our Expanded Access Policy.

Discovery & pre-clinical — beyond the vaccine

Program
Pre-Clinical
POC
Lead Optimization
IND Enabling
MV2C2Humanized anti-survivin IgG · auto-immune disease & cancer
Pre-ClinicalPre-clinical
POCPOCNIH/NINDS-supported — see note below
Lead OptimizationYes
IND EnablingYes
MV377Anti-survivin camelid sdAb · cancer
Pre-ClinicalPre-clinical
POCPOC
Lead OptimizationYes
IND EnablingYes
MV209Anti-survivin CAR-T · cancer
Pre-ClinicalPre-clinical
POCPOCEarly POC

MV2C2 is supported in part by the NIH National Institute of Neurological Disorders and Stroke (NINDS).

Enrolling now

See which SurVaxM studies are open near you.

Full listings, eligibility criteria and sites are maintained on ClinicalTrials.gov rather than duplicated here, so the record always matches the official one.

Search on ClinicalTrials.gov →